Nucleic acid extraction system

Chemagen chemagic MSM I

Chemagen chemagic Magnetic Separation Module I

The chemagic Magnetic Separation Module I (chemagic MSM I) automatically isolates nucleic acids within one hour. Viral RNA from 96 nasal swabs can be isolated simultaneously.

The Chemagen MSM-1 is an automated system for high-throughput nucleic acid (DNA/RNA) isolation.

It utilizes patented Magnetic Bead Technology, in which magnetizable metal rods are immersed in the process solutions to efficiently collect and resuspend the bound particles.

Technical Features & Capacity

Throughput: The system has a modular design and can process 12, 24, or 96 samples simultaneously, depending on the rod head used.

Sample Volume: It offers high flexibility for volumes from 10 µl to 10 ml.

Processing Time:

96 samples (small volumes): approx. 15–60 min.

24 samples (medium volumes): approx. 35–60 min.

12 samples (large volumes): approx. 45–60 min.

Technology: Particle resuspension is achieved by rotating the metal rods at up to 2,000 rpm, enabling high yield and purity without cross-contamination.

System Components & Extensions
Automation: The MSM-1 can be integrated into standard liquid handling units and often features a 6-axis industrial robot for fully automated sample tracking.

Software: The system is controlled by chemagic QA software, which is LIMS-compatible.


Applications

The device is primarily used in research and diagnostics, including:

Biobanking and human genetics
HLA typing
Detection of viruses and bacteria
Extraction from various materials such as whole blood, saliva, serum, or plasma

System Components
Actuators: High-precision linear axes for vertical movement and a rotary axis for mixing
Electromagnet: Central unit for controlling the magnetic attraction to the metal rods
Interfaces: Integrated PC with screen, keyboard, and barcode scanner for sample tracking
Software: chemagic QA software (LIMS-compatible, logging, user management)

Special Features
Cross-contamination protection: The use of disposable protective sleeves (tip combs) for the metal rods prevents contact between samples.

Automation: Can be combined with the chemagic dispenser for automated buffer filling or integrated into liquid handling robots (e.g., Hamilton, Tecan).
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Probe heads: 96
Sample volume: 10 - 400 μL
Number of samples: 1 to 96 samples
TFT monitor, keyboard, and mouse
Year of manufacture: 2007

Dimensions & Setup
Basic machine (W/D/H): approx. 600 x 640 x 950 mm.

Carrier axis (W/D/H): 1940 x 170 x 200 mm (with full expansion and rail system).

Total space requirement: A fully configured system can require up to 2000 x 740 x 800 mm (L/W/H).

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